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Biotech Breakthrough Alert:
Game-Changing Cancer Treatment Offers Windfall Profit Potential for Investors
GT Biopharma, Inc. (Nasdaq: GTBP) has developed a promising cancer therapy that could mean high upside for investors who get into the stock while it’s still beneath Wall Street’s radar
7 Critical Reasons
Why GT Biopharma, Inc. (Nasdaq: GTBP) Could Become the Next High-Upside Biotech Success Story
1) Game-Changing Proprietary Cancer Treatment Platform
GT Biopharma’s revolutionary targeted immunotherapy appears poised to potentially change cancer treatments in a permanent way. That’s because the company’s TriKE® platform is designed to harness and enhance the cancer killing abilities of a patient’s immune system’s natural killer cells. Most impressively, GT Biopharma’s TriKE therapy offers numerous advantages over other treatments as it is less intensive, less expensive and potentially more effective.
2) Multiple Potential Catalysts Ahead to Propel Growth
The company now has more than six pipeline assets in preclinical development, including a Phase 1 trial that has been initiated for its GTB-3650 2nd generation monotherapy. This 2nd generation therapy is an improved version building on the successful trial results from its previous GTB-3550 monotherapy. GT Biopharma estimates that this 2nd generation therapy is potentially 10 to 40 times more effective than its first generation therapy. The company currently has assets in development for the treatment of blood cancers, solid tumors and autoimmune disorders.
3) GT Biopharma is Serving a Massive Addressable Market
According to the experts at Mordor Intelligence, the global cancer therapy market is estimated at $243.67 billion in 2025 and is projected to grow to an astounding $403.99 billion by 2030.[iv] This represents a compound annual growth rate of 10.64% per year…and thanks to its multiple assets in development, GT Biopharma is poised to service multiple segments of this rapidly growing market.
4) Expansive Potential: GT Biopharma’s Platform Technology is Being Evaluated in the Treatment of Blood Cancer, Solid Tumors and Autoimmune Disorders
The company’s TriKE technology is a proprietary platform technology, as the company has an exclusive worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE technology. Its GTB-3650 is the company’s 2nd generation TriKE technology designed to treat blood cancers such as AML and MDS, while its GTB-5550 is designed to treat solid tumors. The company’s GTB-7550 TriKE product is now in development for the treatment of lupus and other autoimmune disorders. Potential treatment of autoimmune disorders means that GT Biopharma would also provide exposure to the global autoimmune disease therapeutics market, which is projected to grow to $116.8 billion by 2032.[v]
5) The Company Appears Poised for a Potentially Significant Increase in Valuation
The analysts at Roth MKM initiated coverage of GT Biopharma in December 2024 and established a 12-month price target of $11 for the company’s shares, which represents a forecasted potential upside of roughly 350% from the share price of $2.38 on 4/2/25. In addition, a glance at some of the company’s closest competitors shows Fate Therapeutics (Nasdaq: FATE) with a market cap of $79.84 million, Nkarta, Inc. (Nasdaq: NKTX) with a market cap of $123.82 million and Innate Pharma S.A. (Nasdaq: IPHA) with a market cap of $185.87 million. Compare those market caps to GT Biopharma (Nasdaq: GTBP) and its roughly $6 million market cap – with $4 million in cash on its balance sheet – and you can see there is potential for significant increase in valuation for the company.
6) GT Biopharma Could be the Next Lucrative Buyout Candidate
Some of GT Biopharma’s closest peers with early-stage NK cell activating technology have already generated a great deal of attention from larger biotech companies leading to a number of multi-million-dollar buyouts. With its impressive proprietary TriKE platform, GT Biopharma could rapidly emerge as the next potentially lucrative “Big Pharma Buyout” candidate.
7) Proven Leadership Team with Deep Immuno-Oncology Experience
The company is guided by an impressive team that brings decades of experience from both the business world as well as the immuno-oncology space. The team’s proven track record of success in biotech, pharma, product development and financing is an ideal combination to help ensure GT Biopharma’s ongoing success.
Little-Known GT Biopharma (Nasdaq: GTBP) Appears Poised to Change Cancer Treatment Forever…and Potentially Deliver High Upside to Early Investors
An exciting – and potentially fast-moving – opportunity is now unfolding in the biotech space.
One under-the-radar company is pioneering a breakthrough cancer treatment that has the potential to disrupt the $243.67 billion cancer treatment market.
And that market is growing rapidly, with experts projecting it to be worth as much as $403.99 billion by 2030.
In the midst of this rapidly growing market, this company’s treatment has the potential to be truly disruptive when it comes to the way cancer is treated.
That’s because its proprietary treatment platform is designed to harness and enhance the cancer killing abilities of a patient’s immune system’s natural killer cells…allowing the body to potentially destroy cancer cells on its own – without surgery, chemotherapy or radiation.
The under-the-radar Nasdaq company developing this potential cancer breakthrough is GT Biopharma, Inc. (Nasdaq: GTBP).
GT Biopharma is a clinical stage immune-oncology company led by a team of leading cancer researchers – including the University of Minnesota’s Dr. Jeffrey Miller – that is in the process of proving the efficacy of a true cancer breakthrough.
How NK Cells Destroy Cancer Cells
This is how a reprogrammed NK cells identifies and kills only cancer cells leaving healthy cells alone. NK cells do not die when killing a cancer cell; instead they continue killing until all cancer cells have been wiped out.
The company is focused on developing innovative therapies based on the company’s proprietary NK cell engager (TriKE) technology. The company’s first generation of this therapy already delivered impressive results in Phase 1 clinical trials…
…and the company has since developed a second generation of this therapy which it estimates to be potentially 10 to 40 times more effective than its first generation therapy.
TriKE therapeutic agents are targeted immunotherapeutic agents that simultaneously react with natural killer (NK) cells and cancer cells to selectively facilitate the killing of cancer cells.
What this means is that TriKE agents effectively mobilize a patient’s own immune system to help target and kill cancer cells – and only cancer cells – again and again.
GT Biopharma’s TriKE therapy addresses the most important aspects of the humoral (antibody) response against cancer, namely:
(1) the ability of antibody to mediate antibody dependent cellular cytotoxicity (ADCC) through CD16…
(2) the ability via IL-15 to mediate in vivo expansion of the immune population to recruit more NK cells and generate an anti-cancer response, and…
(3) recognition of a cancer cell’s target tumor antigen.
With a scalable platform that offers the ability to target a variety of tumor cell markers, TriKE molecules can be used to treat both solid tumors and hematological cancers.
GT Biopharma’s 2nd Generation TriKE Could Be 10 to 40 Times More Effective and Is Now in Phase 1 Clinical Trial
Building on the success of the Phase 1 clinical trials for its first-generation TriKEs, the company is now developing unique precision therapeutic agents using camelid-derived nanobodies.
These drugs, called second-generation TriKEs, leverage the distinct properties of camelid antibodies, which are smaller and more stable when stored (i.e., cold storage not required) than traditional human monoclonal antibodies, allowing for ease of engineering and storage.
These camelid drug candidates are designed to address various cancers and autoimmune disorders, and the versatility of these nanobodies enables them to be engineered for optimal therapeutic effects, offering potential benefits such as reduced side effects and more convenient routes of delivery.
And, as mentioned earlier, the company estimates this second generation TriKE therapy could be 10 to 40 times more effective than its first generation predecessor.
GT Biopharma (Nasdaq: GTBP) has a diversified TriKE therapeutic pipeline targeting several oncology indications and HIV. This includes:
* GTB-3550 TriKE – This is the company’s first-generation TriKE product candidate that was initially evaluated in a first-in-human Phase 1 clinical trial for the treatment of relapsed/refractory acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS). In the completed Phase 1 clinical study, GTB-3550 was shown to be safe and well-tolerated at the dose levels evaluated. The study of GTB-3550 demonstrates clinical proof of concept and provides a framework for the design of future clinical trials of TriKE product candidates.
* GTB-3650 TriKE – This TriKE is being developed for the treatment of CD33 positive leukemias, including AML and MDS. GTB-3650 TriKE is the first TriKE product candidate under development that utilizes camelid nanobody technology. The IND application for GTB-3650 was cleared by the FDA in late June 2024, and the company began study enrollment targeting patients with relapsed/refractory AML and high grade MDS on January 21, 2025.
* GTB-5550 TriKE – The GTB-5550 TriKE product candidate is in development for the treatment of B7H3 positive solid tumor cancers.
* GTB-4550 TriKE – The GTB-4550 TriKE product candidate is in development for the treatment of PD-L1 positive solid tumor cancers.
* GTB-6550 TriKE – The GTB-6550 TriKE product candidate is in development for the treatment of HER2 positive solid tumor cancers.
* GTB-7550 TriKE – The GTB-7550 TriKE product candidate is in development for the treatment of lupus and other autoimmune disorders. Should this TriKE prove effective in trials for the treatment of autoimmune disorders, GT Biopharma could also then become a player in the global autoimmune disease therapeutics market, which is projected to grow to $116.8 billion by 2032.[iii]
Upside Alert: GT Biopharma (Nasdaq: GTBP) Appears to Be Significantly Undervalued
This groundbreaking new, cancer-fighting technology obviously has enormous potential. It offers the promise of potentially making cancer treatment more effective, more affordable and more efficient…
…and it also has the potential to help investors collect potential windfall profits in the event of consistent, positive clinical trial results for its multiple drug candidates.
What type of potential exists for investors with GT Biopharma (Nasdaq: GTBP)?
For starters, take a look at what the professionals have to say:
In December 2024, securities analysts at Roth MKM initiated coverage of GT Biopharma with a “Buy” recommendation.
Roth MKM established a 12-month price target of $11 for the company’s shares, which represents a forecasted potential upside of roughly 350% from the share price of $2.38 on 4/2/25.
Roth MKM analyst Jonathan Aschoff wrote, “We are initiating coverage of GT Biopharma, Inc. (GTBP) with a Buy rating and a 12-month price target of $11 based on a DCF analysis using a 25% discount rate that is applied to all cash flows and the terminal value, which is based on a 5x multiple of our projected 2033 operating income of $113 million. We arrive at this valuation by projecting future revenue from GTB-3650, while we await initial clinical validation with GTB-5550 and GTB-7550.”
And for further indication of the potential that exists for GT Biopharma (Nasdaq: GTBP) to see an increase in valuation, take a quick look at how its valuation compares to some of its competitors.
Compare those market caps to GT Biopharma (Nasdaq: GTBP) and its roughly $6 million market cap – with $4 million in cash on its balance sheet and zero debt – and you can see there is potential for significant increase in valuation for the company.
GT Biopharma Could be the Next
Potentially Lucrative “Big Pharma” Takeover Target
Within the industry, some of GT Biopharma’s closest peers with early-stage NK cell activating technology have already generated a great deal of attention from larger biotech companies.
And when this happens, it can be potentially very lucrative. For example:
These lucrative M&A deals are a great illustration of the value of NK cell engagers in the market. Larger pharmaceutical companies have a long and proven history of “scouting” smaller companies with impressive potential and then moving in for a takeover.
Should that happen with a company like GT Biopharma, Inc. (Nasdaq: GTBP), early investors would be best-positioned to reap the potential rewards.
GT Biopharma is Led by a Proven Team with Deep Immuno-Oncology Experience
One of the more impressive aspects of GT Biopharma is the company’s highly experienced management leading the way.
It’s a team that has a wealth of deep expertise in all stages of oncology drug development that helps position the company for success.
This impressive team includes:
Michael Breen – Executive Chairman, Board of Directors
Michael Breen, an English qualified solicitor/attorney who was formerly the Managing Director of the Sports and Entertainment Division of Bank Insinger de Beaufort N. V., which is a wealth management organization and was part of BNP Paribas Group, one of the world’s largest banks. The holding company Insinger de Beaufort Holdings S.A. was listed on the Luxembourg Stock Exchange. Mr. Breen was also a director and major shareholder of an affiliate of Insinger de Beaufort Holdings S.A.
Jeffrey S. Miller, M.D. – Consulting Senior Medical Director
Dr. Miller is currently a Professor of Medicine at the University of Minnesota. He is the Interim Director of the University of Minnesota Masonic Cancer Center. He has more than 20 years of experience studying the biology of NK cells and other immune effector cells and their use in clinical immunotherapy with over 170 peer-reviewed publications. He is a member of numerous societies such as the American Society of Hematology, the American Association of Immunologists, a member of the American Society of Clinical Investigation since 1999.
Alan L. Urban – Chief Financial Officer
Alan Urban has over 30 years of corporate finance and accounting experience for a variety of public and private companies. Most notably Mr. Urban served as a member of the board of directors of GT Biopharma, Inc. (Nasdaq: GTBP), from mid-2022 to mid-2023; and as Chief Financial Officer for Research Solutions, Inc. (NASDAQ: RSSS), a SaaS and content provider in the scientific, technical and medical information space, for over a decade from 2011 to 2021.
7 Critical Reasons
Why GT Biopharma, Inc. (Nasdaq: GTBP) Could Become the Next High-Upside Biotech Success Story
1) Game-Changing Proprietary Cancer Treatment Platform
GT Biopharma’s revolutionary targeted immunotherapy appears poised to potentially change cancer treatments in a permanent way. That’s because the company’s TriKE® platform is designed to harness and enhance the cancer killing abilities of a patient’s immune system’s natural killer cells. Most impressively, GT Biopharma’s TriKE therapy offers numerous advantages over other treatments as it is less intensive, less expensive and potentially more effective.
2) Multiple Potential Catalysts Ahead to Propel Growth
The company now has more than six pipeline assets in preclinical development, including a Phase 1 trial that has been initiated for its GTB-3650 2nd generation monotherapy. This 2nd generation therapy is an improved version building on the successful trial results from its previous GTB-3550 monotherapy. GT Biopharma estimates that this 2nd generation therapy is potentially 10 to 40 times more effective than its first generation therapy. The company currently has assets in development for the treatment of blood cancers, solid tumors and autoimmune disorders.
3) GT Biopharma is Serving a Massive Addressable Market
According to the experts at Mordor Intelligence, the global cancer therapy market is estimated at $243.67 billion in 2025 and is projected to grow to an astounding $403.99 billion by 2030.[iv] This represents a compound annual growth rate of 10.64% per year…and thanks to its multiple assets in development, GT Biopharma is poised to service multiple segments of this rapidly growing market.
4) Expansive Potential: GT Biopharma’s Platform Technology is Being Evaluated in the Treatment of Blood Cancer, Solid Tumors and Autoimmune Disorders
The company’s TriKE technology is a proprietary platform technology, as the company has an exclusive worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE technology. Its GTB-3650 is the company’s 2nd generation TriKE technology designed to treat blood cancers such as AML and MDS, while its GTB-5550 is designed to treat solid tumors. The company’s GTB-7550 TriKE product is now in development for the treatment of lupus and other autoimmune disorders. Potential treatment of autoimmune disorders means that GT Biopharma would also provide exposure to the global autoimmune disease therapeutics market, which is projected to grow to $116.8 billion by 2032.[v]
5) The Company Appears Poised for a Potentially Significant Increase in Valuation
The analysts at Roth MKM initiated coverage of GT Biopharma in December 2024 and established a 12-month price target of $11 for the company’s shares, which represents a forecasted potential upside of roughly 350% from the share price of $2.38 on 4/2/25. In addition, a glance at some of the company’s closest competitors shows Fate Therapeutics (Nasdaq: FATE) with a market cap of $79.84 million, Nkarta, Inc. (Nasdaq: NKTX) with a market cap of $123.82 million and Innate Pharma S.A. (Nasdaq: IPHA) with a market cap of $185.87 million. Compare those market caps to GT Biopharma (Nasdaq: GTBP) and its roughly $6 million market cap – with $4 million in cash on its balance sheet – and you can see there is potential for significant increase in valuation for the company.
6) GT Biopharma Could be the Next Lucrative Buyout Candidate
Some of GT Biopharma’s closest peers with early-stage NK cell activating technology have already generated a great deal of attention from larger biotech companies leading to a number of multi-million-dollar buyouts. With its impressive proprietary TriKE platform, GT Biopharma could rapidly emerge as the next potentially lucrative “Big Pharma Buyout” candidate.
7) Proven Leadership Team with Deep Immuno-Oncology Experience
The company is guided by an impressive team that brings decades of experience from both the business world as well as the immuno-oncology space. The team’s proven track record of success in biotech, pharma, product development and financing is an ideal combination to help ensure GT Biopharma’s ongoing success.
[i] https://www.mordorintelligence.com/industry-reports/cancer-therapy-market
[ii] https://www.globenewswire.com/news-release/2024/12/13/2996844/0/en/Global-Autoimmune-Disease-Therapeutics-Market-to-Reach-USD-116-81-Billion-by-2032-Growing-at-a-5-52-CAGR-SNS-Insider.html
[iii] https://www.globenewswire.com/news-release/2024/12/13/2996844/0/en/Global-Autoimmune-Disease-Therapeutics-Market-to-Reach-USD-116-81-Billion-by-2032-Growing-at-a-5-52-CAGR-SNS-Insider.html
[iv] https://www.mordorintelligence.com/industry-reports/cancer-therapy-market
[v] https://www.globenewswire.com/news-release/2024/12/13/2996844/0/en/Global-Autoimmune-Disease-Therapeutics-Market-to-Reach-USD-116-81-Billion-by-2032-Growing-at-a-5-52-CAGR-SNS-Insider.html
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